Cause and Etiology of Endometriosis

Cause and Etiology of Endometriosis

 

current theories on endometriosis

 

Current Medical science is not sure of the exact cause of endometriosis, although it has several theories. These theories attempt to explain the disease and the cause, but unfortunately non have been entirely proven, and none actually look at the trigger of the disease; only the effects. Reality might be a combination of the theories (effects) outlined below, or a completely different cause, which is more believable.

 

 

 

 

Theory of Retrograde Menstruation

 

This theory suggests that an altered immune response is a key element in the pathogenesis of endometriosis. The typical profile of a patient with this immunological condition is an increase in humoral immunity (mediated by antibodies) and increased macrophage (a type of cellular “cleaner”) activation but lowered cell mediated immunity as demonstrated by decreased T-cell and natural killer cell responsiveness.
Although this “theory” comes a little closer it does not identify the disease trigger! When one looks at “theories” like this one must be critical in evaluating them.

 

 

 

Theory of Immunologic Dysfunction

 

This theory suggests that an altered immune response is a key element in the pathogenesis of endometriosis. The typical profile of a patient with this immunological condition is an increase in humoral immunity (mediated by antibodies) and increased macrophage (a type of cellular “cleaner”) activation but lowered cell mediated immunity as demonstrated by decreased T-cell and natural killer cell responsiveness.
Although this “theory” comes a little closer it does not identify the disease trigger! When one looks at “theories” like this one must be critical in evaluating them.

This theory merely outlines some of the effects or responses to THE TRUE CAUSE! It does not identify the cause of the disease.

So why do they call it a theory on how the disease develops or occurs? Because they have no idea what science is about! We have a generation of “scientists” that cannot think for themselves! Sorry but I’m not going to sugar coat things for these guys, especially if they think that observing a few effects and placing them together as a “theory” is science!

It would be the same as me looking at a burn mark and making up a theory that the burn occurred because of such and such underlying cause in the skin. They might even point out that there is an increase of this cell type or that chemical (as is the case when you get burned) and lump it all up as a new “condition”. You know what the next logical step for drug companies is?

They claim to spend “millions” in research (in reality they spend a few thousand dollars), and come up with creams and lotions to make your burn “feel” better. In the meantime the real cause, the fact that you came into contact with something really hot, is concealed! In this example you know what the cause of the condition is, because you felt the heat when you touched it, thus nobody can tell you otherwise. What happens when the cause is not known to you? See how this works?

 

 

Theory of Metaplasia

 

Metaplasia is the changing of one normal type of tissue to another normal tissue type.
The colemic wall epithelium gives rise to both the peritoneum and the endometrium. That is, the later two tissues are derived from and arise from the first.
Thus this theory suggests that the colemic epithelium is transformed into endometrial tissue by an unknown stimulus.
This theory might explain why women with total hysterectomy and who are not taking estrogen replacement have endometriosis.
Yes that is correct, they will remove female reproductive organs with the wink of an eye just to prove a point, and when it fails, they still keep using the same method!

Guess what…This “theory” is not a theory on how the disease occurs, it is merely an observation of an effect that the disease might cause.

The true trigger for endometriosis skyrocketing remains unknown! All this theory tells us is that there might be some cells turning into other cells! Great!

 

 

Theory of Remnant Mullerian cells

 

Another theory states that remnant Mullerian cells may remain in the pelvic tissues during development of the Mullerian system.
Müllerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the Müllerian eminence in the primitive urogenital sinus.

In the female, they will develop to form the Fallopian tubes, uterus, cervix, and the upper two-thirds of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.

Under situations of estrogen stimulation, they may be induced to differentiate into functioning endometrial glands and stroma.

This “Theory” is similar to the metaplasia theory, with the source of cells that transform being from a specific type of tissue as outlined.

The cause of the disease is not important to them either, all they are interested in describing is effects the trigger might initiate.

One more thing of interest, “under situations of estrogen stimulation”…There is a clue here…The cells might be triggered by hormonal changes.

 

Genetics

 

Some women may have a genetic predisposition to endometriosis and it has been shown that first-degree relatives of women with this disease are more likely to develop it as well. The endometriosis gene might offer hope- they say.
Here we have a huge issue. These people (sadly even some in the medical and science fields), do not understand how genetics work. A “doctor” will continue to dish out whatever the latest drug on offer is, and think with the prehistoric “education” he received 30 years ago (great for categorising disease but not curing anything!)- Ironically in the end he dies from the same diseases his patients die from. You see, a persons genetics might make a particular situation more probable given a specific environment.

The place we live in, is a specific micro environment of the larger planet.

It has a multitude of processes and events taking place every second, the sum total of which equates to a constant specific environment on the day to day scale of things.

This day to day specific micro climate is subject to gradual change over the years as processes we initiate or nature is responsible for affect the current equilibrium. This equilibrium or balance must not mislead you into thinking it is “healthy” it could be a “sick” balance.

Where is the problem with this “theory”, well they argue that endometriosis might be caused by family genes. After all they have observed that first degree relatives are more probable to suffer with endometriosis as well.

The human being is a complex organism, with thousands of genes, and a lot of “junk” according to current established science. They have no idea what this DNA does you see, so they conveniently call it “junk DNA”! (Now that is serious science- dont you think?)

The idea that there is one gene responsible for endometriosis or cancer or anything is ludicrous.

The environment we live in, in combination with a particular gene set might make endometriosis more likely.

Once the cause of endometriosis is known, then and only then can necessary steps be taken to correct it and allow the body to heal.